The number of women suffering from Alzheimer’s disease is higher than observed in men, and now scientists suppose they know why. A research team from Vanderbilt University Medical Center, Nashville, Tennessee, has recognized gender dissimilarities in how the Alzheimer’s-associated protein tau metastasizes within the brain. Scientists propose that tau disperses through the brain similar to an infection, shifting from neuron to neuron and converting other proteins into irregular tangles that cause the brain cells’ death.
In this study, the researchers utilized information from PET (positron emission tomography) scans of healthy individuals and patients with mild cognitive (mental) impairment to generate a graphical examination of how tau spreads. The scientists discovered that the tau networks’ structure is dissimilar in women and men, with women boasting a huge number of “bridging regions” that link numerous brain areas.
This might facilitate tau to disperse more easily within the brain areas, escalating the pace at which it mounts up and positioning females at greater risk for this particular condition, said the researchers. Further study is required to corroborate that females have a hastened spread of tau. If this is substantiated, then sex-specific methods might be required to thwart Alzheimer’s, as per the scientists. This can comprise earlier treatment, remedial assistance for memory, and/or lifestyle interventions.
Likewise, several older adults who have issues sleeping consume pills to help them sleep. Another recent study, represented at the Alzheimer’s Association International Conference 2019, proposes specific groups of individuals who consume sleep medication might be at a greater threat of developing dementia. Sleep issues are an ordinary indication of dementia. Individuals who are analyzed with Alzheimer’s disease plus other dementias are more prone to get up during the nighttime and become twitchy when they are awake. This indication of dementia can also have a noteworthy influence on those caring for individuals diagnosed with dementia.